International Superstar Soccer 2000

International Superstar Soccer 2000 is a Game Boy Color soccer game, serving as an update to its predecessor. It features a selection of thirty six national teams for play.

The game provides several match formats beyond a standard cup, including league and tournament modes, as well as a dedicated penalty shoot out option. Match duration is adjustable, and the computer opponent offers a challenging range of five difficulty settings. Rules such as fouls, offside calls, and card systems can be toggled, and extra time can be configured.

Visual presentation received significant enhancements for this version.